Chorea and Infections

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Sydenham's Chorea

Sydenham’s chorea is a delayed complication of group Aßhaemolytic streptococcal infections and forms one of the majorcriteria of acute rheumatic fever.It is characterised bychorea, muscular weakness, and a number of neuropsychiatricsymptoms. It is considered to be an autoantibody mediated disorderwith the evidence suggesting that patients with Sydenham’schorea produce antibodies that cross reac...

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Chorea and related disorders.

Chorea refers to irregular, flowing, non-stereotyped, random, involuntary movements that often possess a writhing quality referred to as choreoathetosis. When mild, chorea can be difficult to differentiate from restlessness. When chorea is proximal and of large amplitude, it is called ballism. Chorea is usually worsened by anxiety and stress and subsides during sleep. Most patients attempt to d...

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Huntington's chorea and tryptophan.

Daily use of 7 g l-tryptophan and 70 mg pyridoxine for 14 days led to no deterioration of objectively measured manual motor skills in a small group of patients with Huntington's chorea.

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Enterococcus and Sydenham's Chorea

IF Onle examines the literature on the bacteriology of chorea, one finds that as far back as 1894 a cliplococcus was isolated by Dana from the brain of a fatal case.1 and others have isolated differenit cocci as being the cause of rheutmiatic infectioni, anid some have injected streptococci into rabbits anid prodluced clhoreiform coniditions. In a paper publislhed elsewvhere in this Journal,2 S...

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Huntington's chorea.

The pharmacological treatment of Huntington's chorea has been based on the use of neuroleptic drugs, on the hypothesis that there is a functional dopaminergic hyperactivity in this illness (Agid, 1975). More recently, after the observation of reduced cholinergic and GABAminergic activity at the striatal level in brains of choreic subjects (McGeer et al., 1973; Stahl and Swanson, 1974; Bird and ...

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ژورنال

عنوان ژورنال: The Journal of Nervous and Mental Disease

سال: 1894

ISSN: 0022-3018

DOI: 10.1097/00005053-189410000-00017